Manuscript Number : IJSRST207653

Nucleic Acid Sensors onto Peptide Nucleic Acid (PNA) Surface

Authors(1) :-Dr. Srabani Ghosh

A biosensor is defined as “a device that uses specific biochemical signal mediated by isolated enzymes, immunosystems, tissues, organelles or whole cells to detect chemical compounds usually by electrical, thermal or optical signals” [1]. A sensor comprises of at least two basic steps, first, target detection and second, signal transduction. The target detection element can be a suitable chemical compound or biological molecules such as small peptides, proteins, nucleic acids, carbohydrates etc. Ideally, this entity should exhibit high level of affinity and specificity towards the analytes. For example, antibodies are protein-based binding molecules that have long been used for target recognition because they meet most of the above criteria. Signal transduction elements are responsible for converting molecular recognition events into physically detectable signals such as, optical (e.g., fluorescence), chemical, electrochemical, magnetic, thermal or mechanical changes.

Authors and Affiliations

Dr. Srabani Ghosh
MVJ College of Engineering, Near ITPB, Whitefield, Bangalore, Karnataka, India

DNA, PNA, Biosensor, Au(111), AFM

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Publication Details

Published in : Volume 8 | Issue 1 | January-February 2021
Date of Publication : 2021-01-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 83-93
Manuscript Number : IJSRST207653
Publisher : Technoscience Academy

Print ISSN : 2395-6011, Online ISSN : 2395-602X

Cite This Article :

Dr. Srabani Ghosh , " Nucleic Acid Sensors onto Peptide Nucleic Acid (PNA) Surface", International Journal of Scientific Research in Science and Technology(IJSRST), Print ISSN : 2395-6011, Online ISSN : 2395-602X, Volume 8, Issue 1, pp.83-93, January-February-2021. Available at doi : https://doi.org/10.32628/IJSRST207653    
Journal URL : https://ijsrst.com/IJSRST207653
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